Perskindol
Terpineol

Terpineol

  • Elements of pine resin, obtained from essential oils

Selected Properties

  • Rubefascient
  • Penetration enhancer
  • Terpenes are generally considered to be less toxic with low irritancy potential compared to surfactants and other synthetic skin penetration enhancers32

Mechanism of Action

Terpenes can increase skin permeation by one or more of the mechanisms32

  • Enhancing solubility of the active ingredients into skin fat
  • Dissolution of the lipid / protein structure
  • Elimination of cutaneous micro-elements, responsible for maintaining the barrier

References

  1. B. SAPRA, S. JAIN, A. K. TIWARY, PERCUTANEOUS PERMEATION ENHANCEMENT BY TERPENES: MECHANISTIC VIEW. AAPS J 10, 120-132 (2008).