- Obtained from Rosmarins officinalis flowering aerial parts
- 1,8-Cineole, Camphor and alpha –Pinene are the major chemical compounds33
Mechanism of Action
Anti-inflammatory effect34, 35, 36
- Mild inhibitory activity on 5-lipoxygenase observed with rosemary essential oil
- Inhibition of excessive leucocyte migration and adhesion to damaged tissue
- Animal research concluded that rosemary oil relieves pain by influencing opioid and serotonin receptor activity
- Stimulates receptor function of α1 and α2 adrenergic receptors which improves local blood circulation and relieves pain
- F. M. SOLIMAN, E. A. EL-KASHOURY, M. M. FATHY, M. H. GONAID, ANALYSIS AND BIOLOGICAL ACTIVITY OF THE ESSENTIAL OIL OF ROSMARINUS OFFICINALIS L. FROM EGYPT. FLAVOUR AND FRAGRANCE JOURNAL 9, 29-33 (1994).
- S. Baylac, P. Racine, Inhibition of 5-lipoxygenase by essential oils and other natural fragrant extracts. International Journal of Aromatherapy 13, 138-142 (2003).
- G. A. Nogueira de Melo et al., Rosmarinus officinalis L. essential oil inhibits in vivo and in vitro leukocyte migration. Journal of medicinal food 14, 944-946 (2011).
- I. Takaki et al., Anti-inflammatory and antinociceptive effects of Rosmarinus officinalis L. essential oil in experimental animal models. Journal of medicinal food 11, 741-746 (2008)
- A. L. Martinez, M. E. Gonzalez-Trujano, F. Pellicer, F. J. Lopez-Munoz, A. Navarrete, Antinociceptive effect and GC/MS analysis of Rosmarinus officinalis L. essential oil from its aerial parts. Planta Med 75, 508-511 (2009).
- P. Sagorchev, J. Lukanov, A. M. Beer, Investigations into the specific effects of rosemary oil at the receptor level. Phytomedicine 17, 693-697 (2010).