Perskindol
Lavender Oil

Lavender Oil

  • Obtained from Lavendula angustifolia flowering tops
  • Linalool (9.3% - 68.8%) and Linalyl Acetate (1.2% - 59.4%) are the major chemical compounds43

Selected Properties

  • Anti-inflammatory
  • Analgesic
  • Skin healing

Mechanism of Action

Anti-inflammatory effect44,45

  • Lavender may decrease inflammation by increasing the cell’s protective mechanism against stress-induced damage (Heat Shock Protein 70, HSP70)
  • Effect may be related to a G protein-coupled receptor and/or interference in the system of intracellular second messenger phospholipase C/inositol phosphate

Analgesia45,46,47,48

  • The antinociceptive action of lavender essential oil could be related to opioidergic neurotransmission (it is not involved with inactivation of COX)

Reduction of anxiety and depression49

  • Topical treatment with lavender oil accelerates formation of granulation tissue in the early phase of wound healing (TGF-β is involved in the mechanism)

References

  1. R. PRUSINOWSKA, B. SMIGIELSKI KRZYSZTOF, COMPOSITION, BIOLOGICAL PROPERTIES AND THERAPEUTIC EFFECTS OF LAVENDER (LAVANDULA ANGUSTIFOLIA L). A REVIEW, IN HERBA POLONICA. (2014), VOL. 60, PP. 56.
  2. M. Y. Huang, M. H. Liao, Y. K. Wang, Y. S. Huang, H. C. Wen, Effect of lavender essential oil on LPS-stimulated inflammation. Am J Chin Med 40, 845-859 (2012).
  3. G. L. Silva et al., Antioxidant, analgesic and anti-inflammatory effects of lavender essential oil. Anais da Academia Brasileira de Ciencias 87, 1397-1408 (2015).
  4. V. Hajhashemi, A. Ghannadi, B. Sharif, Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill. J Ethnopharmacol 89, 67-71 (2003).
  5. M. C. Ou, T. F. Hsu, A. C. Lai, Y. T. Lin, C. C. Lin, Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet Gynaecol Res 38, 817-822 (2012).
  6. E. Barocelli et al., Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon “Grosso” essential oil. Life Sci 76, 213-223 (2004).